RAF Typhoon FGR4s have conducted a mission with French warplanes in a coordinated attack targeting an underground arms cache in Syrian territory employed by the Islamic State group (IS), according to the British defence ministry.
The site, identified by surveillance, was assessed as storing arms and explosives, the statement said, and was situated in hills just above the ancient city of Palmyra in central Syria.
"Our fighter planes utilized laser-guided Paveway IV weapons to target a several entry passages down to the site... early reports indicate the target was engaged successfully," officials stated.
There was no evidence of any civilian impact in the strike on Saturday evening and all the aircraft made a safe return, the MoD added.
The British jets were assisted by a Voyager aerial refuelling aircraft.
The Islamic State group - alternatively referred to as Daesh - enforced militant control over large swathes of both Syria and Iraq before its territorial defeat in 2019.
"This operation shows the UK's leading role, and determination to work closely with our allies, to eliminate any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," UK Defence Secretary John Healey said.
British military aircraft have conducted patrols over Syrian airspace to "deter any attempted resurgence" of Islamic State after its military defeat at the battle of Baghuz in the year 2019, the authorities noted.
"I must thank every member of the UK armed forces involved in this operation for their skill and their courage," Healey said. "They were part of a great many UK service members stationed over the festive period. This mission, to eliminate terrorist threats who threaten our way of life, shows how UK forces are always on standby, continuously, keeping Britain secure domestically and powerful internationally."
Last December, the American forces executed what it termed a "massive strike" against Daesh sites in the country, subsequent to an attack resulted in the deaths of two US troops and a civilian interpreter in the Palmyra area.
The United Nations reports IS still maintains roughly 5-7 thousand militants in Syria and Iraq.